The 2021–22 Holy Cross Crusaders men's basketball team represents the College of the Holy Cross in the 2021–22 NCAA Division I men's basketball season.
The Crusaders, led by third-year head coach Brett Nelson, plays their home games at the Hart Center in Worcester, Massachusetts as members of the Patriot League.
Previous season
The Crusaders finished the 2020–21 season 5-11, 5-11 in Patriot League play to finish last place in the North Division and eighth place overall.
They suspended their season after another COVID-19 test within the program and did not play in the Patriot League Tournament.
Roster
Schedule and results
|- !colspan=9 style=|Non-conference regular season
|- !colspan=9 style=|Patriot League regular season
|- References
